Recursive Adaptation

Recursive Adaptation

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Addiction is like an iceberg: most of the harms are below the surface
A visualization of the direct and downstream effects of addiction.
Jun 4 • Nicholas Reville
Making a non-opioid painkiller available to everyone would save Medicare and Medicaid $14.9B and prevent hundreds of thousands of new…
Suzetrigine is sitting on the shelf waiting for its patent to expire, while hundreds of thousands of new opioid addictions are being caused by…
Jun 18 • Nicholas Reville
How can government drive more medication development for addiction? Our work in DC.
CASPR gets FDA acceleration language for SUD into the House Appropriations Committee report.
May 22 • Nicholas Reville
The FDA and a breakthrough for drug repurposing efforts
Finding a path for off-patent drugs to reach patients for new uses
May 14 • Eli Spector and Nicholas Reville
New semaglutide for alcohol use disorder trial shows big drops in drinking
Once-weekly semaglutide versus placebo in patients with alcohol use disorder and comorbid obesity: a randomised, double-blind, placebo-controlled trial…
May 1 • Nicholas Reville
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GLP-1 for Addiction: the Medical Evidence for Opioid, Nicotine, and Alcohol Use Disorder
May 14, 2024 • Nicholas Reville and Zarinah Agnew
Addiction Predictions for 2025 and Beyond
Dec 28, 2024 • Nicholas Reville
Wegovy and Ozempic (semaglutide) are associated with a 50-56% reduction in alcohol addiction
May 30, 2024 • Nicholas Reville
An Innovation Agenda for Addiction
Dec 10, 2024 • Nicholas Reville and Will
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CASPR is hiring
Director of Research, Director of Policy, and Policy Lead
Mar 16 • Eli Spector, Nicholas Reville, and Lindsay Holden
First ever 50-state ranking of online gambling safety
See your state's report card and ranking, from Montana at #1 to Delaware at #50.
Mar 4 • Nicholas Reville
2026 is the year DraftKings will face serious opposition for the first time
Online gambling is the new tobacco: the public is realizing they've been scammed.
Mar 4 • Nicholas Reville
By making suzetrigine cheap, we could cut opioid prescriptions in half
A win / win / win deal for the public, the government, and the drugmaker can cut the Gordian knot of pain prescription tradeoffs.
Feb 10 • Nicholas Reville
NIH High Leverage Trials (HILT) Proposal
Large-scale Research for Repurposing and Supplements
Feb 3 • Nicholas Reville
Preventing online gambling addiction: briefing for state policymakers Feb 3rd
Effective policy interventions to reduce gambling addiction and bankruptcies.
Feb 2 • Nicholas Reville
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