Now, this is really becoming exciting in a very giddy way. I'm a clinical psychologist and I sometimes work with SUDs patients. I therefore appreciate the potential value of this creeping pharmacological revolution in addiction management. But the sceptic in me is also screaming for cases in which GLP-1S was a failure. There're bound to be such cases, right? And we need to understand why they didn't work. Thanks for what you do on this newsletter .
They don’t work for everyone, though for alcohol it seems like nearly everyone sees some reduction, based on patient reports. If you look around on Reddit you’ll see a few stories of less or no reductions in drug use.
I have a friend who hasn't had any effects from Mounjaro, not weight loss or decline in drinking. She has gastroparesis, and I wonder if this has anything to do with why it's not working for her. Maybe it's the medication she takes for it, Domperidone?
Melissa, I'm so happy for you. I've had the same experience. Like you, for the first time in my life I feel like I could have a couple of drinks without going overboard. I would never ever try it because I put my family through too much, not to mention the long-term effects it's had on me.
Now, this is really becoming exciting in a very giddy way. I'm a clinical psychologist and I sometimes work with SUDs patients. I therefore appreciate the potential value of this creeping pharmacological revolution in addiction management. But the sceptic in me is also screaming for cases in which GLP-1S was a failure. There're bound to be such cases, right? And we need to understand why they didn't work. Thanks for what you do on this newsletter .
They don’t work for everyone, though for alcohol it seems like nearly everyone sees some reduction, based on patient reports. If you look around on Reddit you’ll see a few stories of less or no reductions in drug use.
Do we have any idea or hypothesis about these no- or low-response cases? Are there contraindications that we need to be aware of?
I have a friend who hasn't had any effects from Mounjaro, not weight loss or decline in drinking. She has gastroparesis, and I wonder if this has anything to do with why it's not working for her. Maybe it's the medication she takes for it, Domperidone?
It doesn't work for my friend who has gastroparesis and takes Domperidone. (Duplicate post, wanted to reply to you specifically)
Do they take an oral GLP-1 or an injection?
Melissa, I'm so happy for you. I've had the same experience. Like you, for the first time in my life I feel like I could have a couple of drinks without going overboard. I would never ever try it because I put my family through too much, not to mention the long-term effects it's had on me.