3 Comments

Sounds like Sinclair method. similar to using Naltrexone. About 1 hr before you would regularly start drinking.

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This feels like propaganda and drug advertising. Any proposed mechanism for how he went from heavy daily drinking to zero withdrawal symptoms overnight?

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We *really* wish the drug companies cared about offering this for AUD! That's part of our mission-- getting them interested in this population, which they have ignored. I can't wait for the day when we can see drug company ads for GLP-1s to reduce drinking. Hopefully in the next few years.

And I don't know if this guy had withdrawal symptoms or not, but because GLP-1s are broadly anti-inflammatory and have neuro-protective effects, it's possible that those effects mediated the withdrawal. We'll need more research to understand that question better.

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