Recursive Adaptation

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“Overnight, the alcohol noise was gone.”
A patient describes how Ozempic and Mounjaro ended her drinking after all else had failed.
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Noah Davis
New study: GLP-1s associated with lower overdose and alcohol intoxication
40% less likely to overdose and 50% less likely to be intoxicated
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Nicholas Reville
Drinking alcohol reduces the body's natural GLP-1 activity
We are hiring! Plus: better bupe adherence via telehealth, tirzepatide acces battles.
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Nicholas Reville
Hiring: CASPR Strategic Associate
We're looking for someone eager to jump into a fast paced, growing, and strategic public health organization.
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Nicholas Reville
Is the shift from injecting to smoking fentanyl contributing to lower overdose deaths?
Over the past few years, there are indications of a growing trend among opioid users towards smoking rather than injecting fentanyl.
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Nicholas Reville

September 2024

How an addiction medicine doctor has made GLP-1s like Ozempic central to his practice
“I’m now offering GLP-1s to nearly all my substance use disorder patients.”
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Nicholas Reville
 and 
Noah Davis
3
New study finds Ozempic patients have a 42%-68% lower risk of opioid overdose
Patients with OUD taking Ozempic have dramatically lower risk of opioid overdose compared to those taking other diabetes medications
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Nicholas Reville
5
News updates: Oregon policy shows no effect on overdose rates
And a new non-addictive painkiller could be approved by January.
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Nicholas Reville
Debating whether addiction is a ‘brain disease’ gets in the way of making progress
The New York Times ran an article this week, Rethinking Addiction as a Chronic Brain Disease, that dives into the endless debate about which framework…
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Nicholas Reville
2

August 2024

Announcing a coalition for large scale clinical trials of GLP-1RAs for addiction
A unique opportunity for a breakthrough in medicine and public health
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Nicholas Reville
News and Research: "Too Much Cocaine"
“Why does Ozmepic Cure All Diseases?”
 • 
Nicholas Reville

July 2024

New study shows 68% drop in prescriptions for smoking cessation for patients taking Ozempic vs insulin
In a patient health record study, semaglutide was associated with strong reductions in indicators of tobacco use among diabetes patients with a history…
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Nicholas Reville
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