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FDA standards for addiction medicine studies are discouraging the development of medications
A shift away from abstinence-only and other binary metrics is overdue.
Nov 4
•
Nicholas Reville
3
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FDA standards for addiction medicine studies are discouraging the development of medications
recursiveadaptation.com
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October 2024
“On Mounjaro, my daily alcohol cravings are gone. Now I just drink one, 8.4-ounce can of Red Bull a day.”
One patient describes how getting on Mounjaro gave her her freedom back.
Oct 30
•
Noah Davis
4
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“On Mounjaro, my daily alcohol cravings are gone. Now I just drink one, 8.4-ounce can of Red Bull a day.”
recursiveadaptation.com
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“There were some dark days”: Why there have been shortages of naltrexone, a key medication for alcohol use disorder
Our reporting reveals we should blame increased demand, brittle supply chains, and the DEA.
Oct 28
•
Noah Davis
5
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“There were some dark days”: Why there have been shortages of naltrexone, a key medication for alcohol use disorder
recursiveadaptation.com
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News updates: can GLP-1s help people get back to work?
Ozempic reduces alzheimer's risk, street medicine with long-acting antipsychotics, methadone treatment retention, more
Oct 24
•
Nicholas Reville
11
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News updates: can GLP-1s help people get back to work?
recursiveadaptation.com
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1
“It was an immediate obliteration of alcohol and opioid cravings.”
Tirzepatide helped a patient with chronic back pain overcome a cycle of opiate and alcohol overuse.
Oct 22
•
Noah Davis
8
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“It was an immediate obliteration of alcohol and opioid cravings.”
recursiveadaptation.com
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4
What interventions can increase innovation in addiction medicine?
There is virtual no pharmaceutical industry activity for novel addiction medicines.
Oct 21
•
Nicholas Reville
7
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What interventions can increase innovation in addiction medicine?
recursiveadaptation.com
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2
Yesterday was a tipping point
Awareness of GLP-1s for addiction is breaking through to the mainstream.
Oct 18
•
Nicholas Reville
14
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Yesterday was a tipping point
recursiveadaptation.com
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3
“Overnight, the alcohol noise was gone.”
A patient describes how Ozempic and Mounjaro ended her drinking after all else had failed.
Oct 17
•
Noah Davis
19
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“Overnight, the alcohol noise was gone.”
recursiveadaptation.com
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3
New study: GLP-1s associated with lower overdose and alcohol intoxication
40% less likely to overdose and 50% less likely to be intoxicated
Oct 17
•
Nicholas Reville
13
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New study: GLP-1s associated with lower overdose and alcohol intoxication
recursiveadaptation.com
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Drinking alcohol reduces the body's natural GLP-1 activity
We are hiring! Plus: better bupe adherence via telehealth, tirzepatide acces battles.
Oct 10
•
Nicholas Reville
10
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Drinking alcohol reduces the body's natural GLP-1 activity
recursiveadaptation.com
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Hiring: CASPR Strategic Associate
We're looking for someone eager to jump into a fast paced, growing, and strategic public health organization.
Oct 10
•
Nicholas Reville
6
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Hiring: CASPR Strategic Associate
recursiveadaptation.com
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Is the shift from injecting to smoking fentanyl contributing to lower overdose deaths?
Over the past few years, there are indications of a growing trend among opioid users towards smoking rather than injecting fentanyl.
Oct 3
•
Nicholas Reville
6
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Is the shift from injecting to smoking fentanyl contributing to lower overdose deaths?
recursiveadaptation.com
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